EBV and Your Heart

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Researching EBV

Epstein–Barr Virus, or EBV, is one of the most common viruses in the world. By adulthood, about 90 to 95 percent of people have been infected. For most, it causes little to no long-term issues. For others, it can quietly persist in the background and resurface when the body is not functioning optimally.

So what does this have to do with your heart

More than you might expect

What is EBV

EBV is part of the herpesvirus family. Once you are exposed, it remains in your body for life in a dormant state. It primarily infects B lymphocytes, a key part of your immune system, and spreads through saliva. It is best known for causing infectious mononucleosis, especially in teenagers and young adults.

Most people are infected early in life and never know it. Others may experience fatigue, swollen glands, or flu-like symptoms during initial infection. After that, the virus typically stays quiet unless something disrupts immune control.

How is EBV Diagnosed

Diagnosing EBV is not just about detecting the virus. It is about understanding whether it is a recent infection, a past exposure, or potentially reactivated.

The most useful test is an EBV antibody panel. Markers like VCA IgM suggest a recent infection, while VCA IgG and EBNA indicate past exposure. Early Antigen levels may point toward reactivation. A basic monospot test can help in acute illness, but it does not provide the full picture.

Additional findings such as elevated liver enzymes or atypical lymphocytes can support the diagnosis, but they are not specific.

How Common is EBV

EBV is nearly universal. The vast majority of adults carry it, often without symptoms. Many people are exposed in childhood, when symptoms are mild or nonexistent. When infection occurs later, particularly in adolescence, it is more likely to present as mono.

This is important because simply testing positive for EBV does not mean it is causing disease. It means you are human.

EBV and Cardiovascular Disease

There is growing research linking EBV to cardiovascular conditions. The virus has been detected in arterial plaque, suggesting a role in vascular inflammation. It has also been associated with myocarditis, pericarditis, and even certain arrhythmias.

In some cases, EBV may contribute to endothelial dysfunction, which affects how blood vessels relax and regulate blood flow. This can impact nitric oxide signaling and overall vascular health.

These associations are important, but they are often misinterpreted.

EBV is Not the Root Cause

If EBV were the root cause of heart disease, nearly everyone would have cardiovascular problems. That is clearly not the case.

The real issue is not the presence of the virus. The issue is the body losing control over it.

When the internal environment is healthy, EBV stays dormant. When that environment is disrupted, the virus may reactivate and contribute to inflammation.

So the question is not whether you have EBV. The question is why your immune system is not keeping it in check.

What Actually Matters

Immune dysfunction does not happen randomly. It is driven by underlying factors that weaken the body’s ability to regulate infections.

These include poor nutrition, toxin exposure, chronic stress, lack of quality sleep, circadian disruption, gut imbalance, and micronutrient deficiencies.

When these factors are present, the immune system becomes overwhelmed or dysregulated. This creates an opportunity for latent viruses like EBV to become active again.

A Better Approach: Test Don’t Guess

Instead of blaming the virus, the focus should be on identifying why the body is vulnerable.

This is where a Test Don’t Guess approach becomes essential. Looking at inflammation markers, oxidative stress, nutrient levels, gut health, toxin burden, and fatty acid balance provides real answers.

This allows for a targeted strategy that supports the body rather than chasing symptoms.

Supporting Your Body and Your Heart

The goal is not to eliminate EBV. The goal is to restore the internal environment so your body can control it naturally.

That starts with real food, especially nutrient-dense options like wild seafood rich in omega-3 fats. It includes prioritizing sleep, aligning with natural light cycles, reducing toxic exposures, and supporting gut health.

When you do this, you strengthen immune function and improve vascular health at the same time.

And give your body what it needs to protect your heart for the long run.

Click HERE for our recommended comprehensive test panel.

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About Dr. Keith Smigiel NP, DC

Dr. Keith Smigiel

Dr. Keith Smigiel is a regenerative medicine physician and pain management specialist. He takes an integrative approach to medicine, focusing on customized solutions tailored to individual needs. Using advanced, non-surgical treatments, Dr. Smigiel stimulates your body’s ability to naturally heal itself.

Dr. Smigiel helps people suffering from conditions such as chronic pain and erectile dysfunction, to hair loss and weight gain. Combining treatments such as PRP Therapy, Ozone, Neural Prolotherapy, and IV Infusions with functional rehabilitation, he helps you look and feel better.

He heals the body, instead of just treating the symptoms!

With his professional qualifications as a certified family nurse practitioner, a doctor of chiropractic, and a fellow of the International Academy of Medical Acupuncture, Dr. Smigiel offers patients comprehensive care from a broad perspective of conventional and alternative medicine. He also has extensive experience in functional rehabilitation and chronic pain management.

Dr. Smigiel is married to Angela and has two children, Sophia and Larz. When he’s not busy helping patients, he enjoys hiking, mountain biking, motocross, and boating.

About Dr. Lauren Lattanza NMD, FACC

Dr. Lattanza Office Visit with Patient

As a Naturopathic Physician, I am trained to treat the whole person and get to the root cause of disease.

I went to Arizona State University where I graduated with a bachelor’s degree in psychology with a depth in physiology and minor in Spanish. After my undergraduate degree I was working on prerequisite classes towards medical school, which is when I came to learn that my values identified best with the principles of naturopathic medicine. I knew that I wanted to help patients identify the causes of disease and be able to offer treatments which would improve their health rather than simply treating symptoms.

I dedicated the next 4 years to the Southwest College of Naturopathic Medicine in Tempe, Arizona where I attained my Doctorate of Naturopathic Medicine. I served as Class President all 4 years, Board of Trustees – Student Trustee, spoke as the Club President for our branch of Toastmasters, and was voted by my peers and attending physicians to earn the Outstanding Leadership Award for the Class of 2020. Throughout medical school I took it upon myself to work alongside MDs, DOs, chiropractors, and functional medicine practitioners in addition to naturopathic physicians.

As a Spanish speaking student, I was able to volunteer with community clinics around Phoenix and provide free healthcare to low-income families. Due to this combined exposure, I came to find my passion in treating cardiometabolic and digestive disorders that are all too common, yet largely preventable. I took the opportunity to learn the broad spectrum of healthcare so I can ensure that I am able to provide my patients with the best options.

About Dr. Jack Wolfson DO, FACC

Dr. Wolfson Office Visit with Patient

Dr. Jack Wolfson is a cardiologist, Amazon best-selling author, husband, father, and the nation’s #1 Natural Heart Doctor.

For more than two decades, more than one million people have enjoyed the warmth, compassion, and transformational power of his natural heart health courses and events.

Dr. Wolfson is the founder of Natural Heart Doctor Scottsdale, his heart health practice in Arizona, and Natural Heart Doctor, an online resource center with natural health information. Doctors from across the globe reach out to Dr. Wolfson for training and education in holistic health practices.

He has been named one of America’s Top Functional Medicine Doctors and is a five-time winner of the Natural Choice Awards as a holistic M.D. Dr. Wolfson’s work has been covered by more than 100 media outlets, including NBC, CNN, and the Washington Post. His book “The Paleo Cardiologist: The Natural Way to Heart Health” was an Amazon #1 best-seller.

Dr. Wolfson and his wife Heather have four children and are committed to making the world a better place to live. They provide for those in need (including animals) and support natural health causes through their philanthropic efforts.

Chiropractic

Our chiropractor is an expert at adjustments and holistic chiropractic care and works closely in conjunction with the other health care experts at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

IV Therapy

We use specially formulated natural vitamins and minerals that are injected into a vein to prevent or treat dehydration. Ideal for people in Arizona.

Call (480) 535-6844 for details and scheduling.

Acupuncture

Stimulate your body’s natural healing abilities and promote physical and emotional well-being with acupuncture at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

Health Coaching

Our health coaches use evidence based skillful conversation, clinical interventions, and strategies to engage you actively and safely in health behavior changes.

Call (480) 535-6844 for details and scheduling.

Cardio Tests

We use the most advanced testing in the world to assess heart health and to identify the root cause of your health issues.

Call (480) 535-6844 for details and scheduling.

Office Visits

Schedule an office visit with one of our cardiologists, holistic physicians, chiropractor, or health coaches.

Call (480) 535-6844 for details and scheduling.

Frequently Asked Questions

I’d like to receive an online second opinion from Natural Heart Doctor. What do I do next?

You can initiate a second opinion online through our website at any time. To begin, select the team member you’d like to speak with and open an account.

Click here for cardiologist Dr. Jack Wolfson.

Naturopathic Medical Doctor Dr. Lauren Lattanza. Get details.

Naturopathic Medical Doctor Dr. Tonia Rainier. Get details.

Click here for  Natural Heart Doctor Health Coach.

Alternatively, you can email health@naturalheartdoctor.com. A member of our care team will help guide you through the process of starting a second opinion.

What is the cost of a Natural Heart Doctor Online Second Opinion?

The cost for most second opinions varies by team member. This fee includes information collection, a phone or video consultation, a second opinion from a Natural Heart Doctor specialist and guidance throughout the process from your personal Care Team at Natural Heart Doctor.

Cardiologist Dr. Jack Wolfson’s Second Opinion Fee is $1500.

Holistic Physician’s Dr. Lauren Lattanza’s Second Opinion Fee is $250.

Naturopathic Physician Dr. Tonia Rainier’s Second Opinion Fee is $250.

Note: We apply the Online Second Opinion Call fee as a credit to any future consultations with Natural Heart Doctor, should you choose them.

Will my insurance cover the cost of a Natural Heart Doctor Online Second Opinion?

Most likely, no. Most health plans do not cover online second opinions or consultations. You are responsible for the cost of our second opinion. Natural Heart Doctor cannot file a claim with your insurance carrier, nor can we provide a procedure (CPT) code for this service.

What is the timeline to receive an online second opinion?

We do our best to schedule your second opinion as quickly as possible. Typically, it takes 5 to 7 business days after your information has been collected to receive your phone or video online second opinion.

What information do you need in advance of our call?

Our office will send you a short questionnaire to complete and return. We DO NOT need your complete medical records.

How many questions can I ask the expert during our call?

You may ask a maximum of five questions. This is to ensure that the expert has sufficient time to devote to each question. All questions must be finalized before your online meeting.

What should I expect to receive once my second opinion is complete?

You will receive a summary of our discussion along with our second opinion. The second opinion will be in written form. After you have reviewed the second opinion, a Natural Heart Doctor clinician will follow up with you by phone to address general medical questions about the information provided in the second opinion.

What if I have follow-up questions for the expert after I have reviewed my second opinion?

If you have a clarifying question about an expert’s response to one of the questions in your second opinion, and the Natural Heart Doctor clinician is unable to address it, then you may request a follow up session for an additional fee. 

Is my medical and payment information secure?

Natural Heart Doctor is strongly committed to protecting the privacy and security of all our patients. Our website meets all federal requirements for protecting personal health information under the Health Insurance Portability and Accountability Act (HIPAA). All financial transactions are processed by Natural Heart Doctor securely using industry standard payment processing tools.

I would rather visit Natural Heart Doctor for an in-person appointment. What should I do next?

If you would prefer an in-person appointment at Natural Heart Doctor instead of an online second opinion, please call (480) 535-6844 for details and scheduling.

Can I schedule a follow up appointment with the specialist who provided my online second opinion?

Yes, we’re happy to help you on an extended basis. Our clinician can discuss options with you when presenting our second opinion summary.