Insulin: What You Need to Know

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Insulin Resistance write on a book with keywords

Insulin is one of the most important hormones in the body, yet few people truly understand its critical role in long-term health. Whether you’re concerned about blood sugar, weight, heart disease, or energy levels—insulin is involved. At Natural Heart Doctor, we believe that understanding insulin is a vital part of living your best, healthiest life. Here’s what you need to know.


What Is Insulin?

Insulin is a hormone produced by your pancreas that acts like a key. Its main job is to unlock your cells so that sugar (glucose) in your bloodstream can enter and be used for energy. After you eat, especially a meal high in carbohydrates, your blood sugar rises. In response, your pancreas releases insulin to bring sugar levels back down to a safe range by moving glucose into your cells or storing it for later use.


What Does Insulin Do?

Insulin has far-reaching effects throughout the body. Some of its primary functions include:

  • Regulating blood sugar: It lowers blood glucose by helping sugar enter cells.
  • Storing nutrients: Insulin promotes fat and glycogen storage for future energy use.
  • Preventing fat breakdown: When insulin is high, the body is less likely to burn fat.
  • Supporting protein synthesis: Insulin helps build and repair tissues.

But insulin doesn’t work in isolation—it has major downstream effects on other hormones and systems in the body:

Hormonal Imbalance

When insulin levels are elevated, it can disrupt the balance of other critical hormones:

  • Testosterone and estrogen: High insulin can increase the conversion of testosterone into estrogen in both men and women, contributing to hormonal imbalances, low libido, and conditions like PCOS.
  • Cortisol: Insulin resistance and blood sugar swings can overstimulate cortisol, the stress hormone, which in turn worsens insulin resistance—a vicious cycle.
  • Leptin and ghrelin: Insulin influences appetite-regulating hormones, making it harder to feel full and easier to overeat, especially sugary or carb-heavy foods.
  • Thyroid hormones: Insulin resistance is linked to poor thyroid function and can slow metabolism.

Kidney Function and Blood Pressure

Insulin also affects kidney function by promoting sodium retention. When insulin levels are elevated:

  • The kidneys hold on to more sodium.
  • This leads to increased water retention.
  • The result is elevated blood pressure and extra strain on the heart.

This is one of the major ways that insulin resistance contributes to hypertension, edema (fluid retention), and cardiovascular disease. It’s also why many people see their blood pressure improve dramatically with better insulin control.


What Makes Insulin Levels Go Too High?

Chronically high insulin—known as hyperinsulinemia—is driven mostly by diet and lifestyle. The most common causes include:

  • Eating too frequently (especially snacking between meals)
  • High carbohydrate, alcohol and sugar intake
  • Sedentary lifestyle
  • Poor sleep
  • Chronic stress
  • Exposure to toxins and endocrine disruptors

Over time, the constant demand for insulin can wear down your cells’ ability to respond. This is known as insulin resistance.


Why Does Insulin Resistance Occur?

Insulin resistance happens when your cells stop responding effectively to insulin’s signal. It’s like your body starts ignoring the hormone, even though there’s plenty of it around.

As a result, your pancreas pumps out even more insulin to try to get the job done. This leads to even higher insulin levels and higher blood sugar—setting the stage for prediabetes, type 2 diabetes, and even cardiovascular disease.

Insulin resistance is at the root of many modern health problems, including:

  • Weight gain and difficulty losing weight
  • Fatty liver
  • High blood pressure
  • Elevated cholesterol and triglycerides
  • Polycystic ovary syndrome (PCOS)
  • Brain fog and cognitive decline

How the 100 Year Heart Method Helps Improve Insulin

At Natural Heart Doctor, we developed the 100 Year Heart Method to help people live vibrant, healthy lives free from chronic disease—and insulin regulation is a critical part of that.

Here’s how our method works to improve insulin sensitivity naturally:

  1. Thrival Nutrition: A diet rich in pasture-raised animal products, healthy fats, wild seafood, and low-glycemic fruits and vegetables supports stable blood sugar and reduces the insulin burden. We avoid processed carbs, sugars, seed oils, and artificial ingredients that spike insulin and promote resistance.
  2. Thrival Lifestyle: Daily movement, quality sleep, sunlight exposure, and stress reduction all improve your body’s ability to use insulin effectively. Our protocols help you lower inflammation and reset your circadian rhythm, which are essential for metabolic health.
  3. Thrival Biohacking: Tools like intermittent fasting, cold exposure, sauna therapy, and grounding enhance insulin sensitivity and metabolic flexibility.
  4. Thrival UltraDiagnostics: We test—not guess. Our vibrant micronutrient, inflammation, and oxidative stress panels help identify the root causes of insulin resistance and personalize your path to healing.

Natural Supplements That Support Healthy Insulin Function

In addition to a healthy lifestyle, we recommend specific supplements that have proven benefits in improving insulin sensitivity:

Berberine

Berberine is a plant-based compound that works similarly to the drug metformin—but naturally and without side effects. It helps:

  • Lower blood sugar
  • Reduce insulin levels
  • Improve lipid profiles
  • Support weight loss

Studies show berberine can significantly improve insulin resistance and metabolic health, making it a powerful tool in our supplement arsenal.

Berberine, along with 6 other herbal nutrients, can be found in OptiLipid, the PERFECT supplement for people with insulin resistance or diabetes. 

Other Supportive Nutrients

  • Magnesium – essential for insulin receptor function
  • Omega-3 fatty acids – reduce inflammation and improve glucose uptake

Our formulas are carefully crafted with high-quality, bioavailable ingredients to support your body’s natural healing abilities.


The Bottom Line

Insulin is a master hormone that influences your energy, weight, blood pressure, brain, fertility, and more. When it’s balanced, you thrive. When it’s out of control, your health suffers.

With the 100 Year Heart Method, we help you reclaim control of your metabolism—naturally and effectively. Through nutrition, lifestyle, advanced testing, and targeted supplements like berberine, you can reset your body’s insulin response and pave the way to a healthier, longer life.

Want to know your insulin status? We offer comprehensive at-home tests that measure insulin, blood sugar, inflammation, and more—so you can start your healing journey today. The Advanced Cardiovascular Analysis contains fasting insulin and more. This is also available inside Level 1 and the CHAT panel. 

Your heart, your hormones, your health—start with insulin. Let us guide you.

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About Dr. Keith Smigiel NP, DC

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Dr. Keith Smigiel is a regenerative medicine physician and pain management specialist. He takes an integrative approach to medicine, focusing on customized solutions tailored to individual needs. Using advanced, non-surgical treatments, Dr. Smigiel stimulates your body’s ability to naturally heal itself.

Dr. Smigiel helps people suffering from conditions such as chronic pain and erectile dysfunction, to hair loss and weight gain. Combining treatments such as PRP Therapy, Ozone, Neural Prolotherapy, and IV Infusions with functional rehabilitation, he helps you look and feel better.

He heals the body, instead of just treating the symptoms!

With his professional qualifications as a certified family nurse practitioner, a doctor of chiropractic, and a fellow of the International Academy of Medical Acupuncture, Dr. Smigiel offers patients comprehensive care from a broad perspective of conventional and alternative medicine. He also has extensive experience in functional rehabilitation and chronic pain management.

Dr. Smigiel is married to Angela and has two children, Sophia and Larz. When he’s not busy helping patients, he enjoys hiking, mountain biking, motocross, and boating.

About Dr. Lauren Lattanza NMD, FACC

Dr. Lattanza Office Visit with Patient

As a Naturopathic Physician, I am trained to treat the whole person and get to the root cause of disease.

I went to Arizona State University where I graduated with a bachelor’s degree in psychology with a depth in physiology and minor in Spanish. After my undergraduate degree I was working on prerequisite classes towards medical school, which is when I came to learn that my values identified best with the principles of naturopathic medicine. I knew that I wanted to help patients identify the causes of disease and be able to offer treatments which would improve their health rather than simply treating symptoms.

I dedicated the next 4 years to the Southwest College of Naturopathic Medicine in Tempe, Arizona where I attained my Doctorate of Naturopathic Medicine. I served as Class President all 4 years, Board of Trustees – Student Trustee, spoke as the Club President for our branch of Toastmasters, and was voted by my peers and attending physicians to earn the Outstanding Leadership Award for the Class of 2020. Throughout medical school I took it upon myself to work alongside MDs, DOs, chiropractors, and functional medicine practitioners in addition to naturopathic physicians.

As a Spanish speaking student, I was able to volunteer with community clinics around Phoenix and provide free healthcare to low-income families. Due to this combined exposure, I came to find my passion in treating cardiometabolic and digestive disorders that are all too common, yet largely preventable. I took the opportunity to learn the broad spectrum of healthcare so I can ensure that I am able to provide my patients with the best options.

About Dr. Jack Wolfson DO, FACC

Dr. Wolfson Office Visit with Patient

Dr. Jack Wolfson is a cardiologist, Amazon best-selling author, husband, father, and the nation’s #1 Natural Heart Doctor.

For more than two decades, more than one million people have enjoyed the warmth, compassion, and transformational power of his natural heart health courses and events.

Dr. Wolfson is the founder of Natural Heart Doctor Scottsdale, his heart health practice in Arizona, and Natural Heart Doctor, an online resource center with natural health information. Doctors from across the globe reach out to Dr. Wolfson for training and education in holistic health practices.

He has been named one of America’s Top Functional Medicine Doctors and is a five-time winner of the Natural Choice Awards as a holistic M.D. Dr. Wolfson’s work has been covered by more than 100 media outlets, including NBC, CNN, and the Washington Post. His book “The Paleo Cardiologist: The Natural Way to Heart Health” was an Amazon #1 best-seller.

Dr. Wolfson and his wife Heather have four children and are committed to making the world a better place to live. They provide for those in need (including animals) and support natural health causes through their philanthropic efforts.

Chiropractic

Our chiropractor is an expert at adjustments and holistic chiropractic care and works closely in conjunction with the other health care experts at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

IV Therapy

We use specially formulated natural vitamins and minerals that are injected into a vein to prevent or treat dehydration. Ideal for people in Arizona.

Call (480) 535-6844 for details and scheduling.

Acupuncture

Stimulate your body’s natural healing abilities and promote physical and emotional well-being with acupuncture at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

Health Coaching

Our health coaches use evidence based skillful conversation, clinical interventions, and strategies to engage you actively and safely in health behavior changes.

Call (480) 535-6844 for details and scheduling.

Cardio Tests

We use the most advanced testing in the world to assess heart health and to identify the root cause of your health issues.

Call (480) 535-6844 for details and scheduling.

Office Visits

Schedule an office visit with one of our cardiologists, holistic physicians, chiropractor, or health coaches.

Call (480) 535-6844 for details and scheduling.

Frequently Asked Questions

I’d like to receive an online second opinion from Natural Heart Doctor. What do I do next?

You can initiate a second opinion online through our website at any time. To begin, select the team member you’d like to speak with and open an account.

Click here for cardiologist Dr. Jack Wolfson.

Naturopathic Medical Doctor Dr. Lauren Lattanza. Get details.

Naturopathic Medical Doctor Dr. Tonia Rainier. Get details.

Click here for  Natural Heart Doctor Health Coach.

Alternatively, you can email health@naturalheartdoctor.com. A member of our care team will help guide you through the process of starting a second opinion.

What is the cost of a Natural Heart Doctor Online Second Opinion?

The cost for most second opinions varies by team member. This fee includes information collection, a phone or video consultation, a second opinion from a Natural Heart Doctor specialist and guidance throughout the process from your personal Care Team at Natural Heart Doctor.

Cardiologist Dr. Jack Wolfson’s Second Opinion Fee is $1500.

Holistic Physician’s Dr. Lauren Lattanza’s Second Opinion Fee is $250.

Naturopathic Physician Dr. Tonia Rainier’s Second Opinion Fee is $250.

Note: We apply the Online Second Opinion Call fee as a credit to any future consultations with Natural Heart Doctor, should you choose them.

Will my insurance cover the cost of a Natural Heart Doctor Online Second Opinion?

Most likely, no. Most health plans do not cover online second opinions or consultations. You are responsible for the cost of our second opinion. Natural Heart Doctor cannot file a claim with your insurance carrier, nor can we provide a procedure (CPT) code for this service.

What is the timeline to receive an online second opinion?

We do our best to schedule your second opinion as quickly as possible. Typically, it takes 5 to 7 business days after your information has been collected to receive your phone or video online second opinion.

What information do you need in advance of our call?

Our office will send you a short questionnaire to complete and return. We DO NOT need your complete medical records.

How many questions can I ask the expert during our call?

You may ask a maximum of five questions. This is to ensure that the expert has sufficient time to devote to each question. All questions must be finalized before your online meeting.

What should I expect to receive once my second opinion is complete?

You will receive a summary of our discussion along with our second opinion. The second opinion will be in written form. After you have reviewed the second opinion, a Natural Heart Doctor clinician will follow up with you by phone to address general medical questions about the information provided in the second opinion.

What if I have follow-up questions for the expert after I have reviewed my second opinion?

If you have a clarifying question about an expert’s response to one of the questions in your second opinion, and the Natural Heart Doctor clinician is unable to address it, then you may request a follow up session for an additional fee. 

Is my medical and payment information secure?

Natural Heart Doctor is strongly committed to protecting the privacy and security of all our patients. Our website meets all federal requirements for protecting personal health information under the Health Insurance Portability and Accountability Act (HIPAA). All financial transactions are processed by Natural Heart Doctor securely using industry standard payment processing tools.

I would rather visit Natural Heart Doctor for an in-person appointment. What should I do next?

If you would prefer an in-person appointment at Natural Heart Doctor instead of an online second opinion, please call (480) 535-6844 for details and scheduling.

Can I schedule a follow up appointment with the specialist who provided my online second opinion?

Yes, we’re happy to help you on an extended basis. Our clinician can discuss options with you when presenting our second opinion summary.