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L-Arginine for Cardiovascular Health and More

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L-Arginine is an amino acid crucial for various physiological functions, particularly noted for its significant impact on cardiovascular health. This naturally occurring compound plays a pivotal role in the body’s production of nitric oxide (NO), a key molecule involved in vasodilation, or the widening of blood vessels. Here’s a detailed look at how L-Arginine benefits health, supported by scientific research.

What is L-Arginine?

L-Arginine is classified as a semi-essential or conditionally essential amino acid, meaning while the body can produce it under normal circumstances, supplementation may be necessary during certain health conditions or stages of life. It is found in foods such as red meat, poultry, fish, dairy products, and certain plant sources like nuts and seeds.

How Does L-Arginine Work?

The primary mechanism through which L-Arginine benefits cardiovascular health is its conversion into nitric oxide. Nitric oxide acts as a vasodilator, relaxing the inner muscles of blood vessels and allowing them to widen. This dilation promotes better blood flow throughout the body, which is crucial for maintaining healthy blood pressure and cardiovascular function. Additionally, nitric oxide helps prevent platelets from clumping together, reducing the risk of clot formation.

Scientific Studies Supporting L-Arginine

Numerous studies have explored the cardiovascular benefits of L-Arginine:

1. Blood Pressure Regulation: Research has shown that L-Arginine supplementation can help lower blood pressure in individuals with hypertension by improving endothelial function and enhancing nitric oxide production.

2. Improved Exercise Performance: Some studies suggest that L-Arginine supplementation may improve exercise tolerance in individuals with cardiovascular conditions by increasing blood flow to muscles and reducing the oxygen cost of exercise.

3. Reduction in Angina Symptoms: L-Arginine has been studied for its potential to reduce symptoms of angina (chest pain) by improving blood flow to the heart muscle.

4. Endothelial Function: L-Arginine has been shown to enhance endothelial function, which is critical for maintaining healthy blood vessels and preventing the development of atherosclerosis. 

5. Erectile Function – As a vasodilator, evidence suggests that arginine helps with erectile function in those with mild/moderate ED (erectile dysfunction). 

What Else Does L-Arginine Support? 

L-Arginine, an amino acid crucial for cardiovascular health, also offers significant benefits for several other key areas of the body, including the brain, kidneys, liver, and gastrointestinal system. Here’s a deeper dive into how L-Arginine supports overall health beyond cardiovascular benefits:

1. Brain Health:

L-Arginine plays a role in supporting cognitive function and overall brain health. It aids in the production of nitric oxide, which helps regulate cerebral blood flow and neurotransmission. Improved blood flow to the brain can enhance cognitive abilities such as memory, learning, and focus. Studies suggest that L-Arginine may have neuroprotective effects, potentially reducing the risk of neurodegenerative diseases.

2. Kidney Function:

The kidneys play a crucial role in filtering waste and maintaining fluid balance in the body. L-Arginine supports kidney function by promoting vasodilation and improving blood flow to these organs. This enhanced blood flow can help optimize renal function and may be beneficial in conditions affecting kidney health.

3. Liver Health:

The liver is responsible for detoxification, metabolism, and synthesis of essential molecules in the body. L-Arginine aids in detoxification processes by supporting the liver’s ability to metabolize toxins and waste products. It also plays a role in ammonia detoxification, which is crucial for liver health. Additionally, L-Arginine may help protect liver cells from damage and support overall liver function.

4. Gastrointestinal Health:

L-Arginine supports gastrointestinal health through several mechanisms. It helps maintain healthy blood flow to the digestive tract, promoting nutrient absorption and optimal digestive function. L-Arginine’s role in nitric oxide production can also contribute to maintaining the integrity of the gastrointestinal lining, which is essential for preventing conditions such as leaky gut syndrome. Some studies suggest that L-Arginine may have beneficial effects in managing conditions like inflammatory bowel disease (IBD).

Sources of L-Arginine

While L-Arginine can be obtained through dietary sources such as meat, dairy, nuts, and legumes, supplementation may be considered to achieve therapeutic doses. L-Arginine supplements are available in various forms, including capsules, powders, and liquids.

L-arginine works best in combination with L-citrulline and L-taurine. That is why we made our product Vessel Support. Learn more about Vessel Support here

What About Herpes Outbreaks? 

There has been concern about arginine supplements and food sources leading to herpes outbreaks. Personally, I have never seen this with our Vessel Support. 

If you are Eating Well, Living Well, and Thinking Well, I don’t expect a problem. 

You can always use lysine to counteract this situation. 


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He heals the body, instead of just treating the symptoms!

With his professional qualifications as a certified family nurse practitioner, a doctor of chiropractic, and a fellow of the International Academy of Medical Acupuncture, Dr. Smigiel offers patients comprehensive care from a broad perspective of conventional and alternative medicine. He also has extensive experience in functional rehabilitation and chronic pain management.

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About Dr. James Kneller, M.D., Ph.D., FHRS

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Dr. James Kneller is one of the nation’s leading heart rhythm specialists. Dr. Kneller is certified by the American Board of Internal Medicine (ABIM) in Clinical Cardiac Electrophysiology, Cardiovascular Disease, and Internal Medicine.

As a Fellow of the Heart Rhythm Society (FHRS) and Certified Cardiac Device Specialist (CCDS), Kneller provides comprehensive patient care, combining best medical practice with invasive procedures using state-of-the-art technologies to treat heart rhythm disorders.

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About Dr. Lauren Lattanza NMD, FACC

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I went to Arizona State University where I graduated with a bachelor’s degree in psychology with a depth in physiology and minor in Spanish. After my undergraduate degree I was working on prerequisite classes towards medical school, which is when I came to learn that my values identified best with the principles of naturopathic medicine. I knew that I wanted to help patients identify the causes of disease and be able to offer treatments which would improve their health rather than simply treating symptoms.

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About Dr. Jack Wolfson DO, FACC

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Dr. Jack Wolfson is a board-certified cardiologist, Amazon best-selling author, husband, father, and the nation’s #1 Natural Heart Doctor.

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Our chiropractor is an expert at adjustments and holistic chiropractic care and works closely in conjunction with the other health care experts at Natural Heart Doctor.

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We use specially formulated natural vitamins and minerals that are injected into a vein to prevent or treat dehydration. Ideal for people in Arizona.

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Stimulate your body’s natural healing abilities and promote physical and emotional well-being with acupuncture at Natural Heart Doctor.

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Our health coaches use evidence based skillful conversation, clinical interventions, and strategies to engage you actively and safely in health behavior changes.

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We use the most advanced testing in the world to assess heart health and to identify the root cause of your health issues.

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Frequently Asked Questions

I’d like to receive an online second opinion from Natural Heart Doctor. What do I do next?

You can initiate a second opinion online through our website at any time. To begin, select the team member you’d like to speak with and open an account.

Click here for cardiologist Dr. Jack Wolfson.

Naturopathic Medical Doctor Dr. Lauren Lattanza. Get details.

Naturopathic Medical Doctor Dr. Tonia Rainier. Get details.

Click here for  Natural Heart Doctor Health Coach.

Alternatively, you can email A member of our care team will help guide you through the process of starting a second opinion.

What is the cost of a Natural Heart Doctor Online Second Opinion?

The cost for most second opinions varies by team member. This fee includes information collection, a phone or video consultation, a second opinion from a Natural Heart Doctor specialist and guidance throughout the process from your personal Care Team at Natural Heart Doctor.

Cardiologist Dr. Jack Wolfson’s Second Opinion Fee is $1500.

Holistic Physician’s Dr. Lauren Lattanza’s Second Opinion Fee is $250.

Naturopathic Physician Dr. Tonia Rainier’s Second Opinion Fee is $250.

Note: We apply the Online Second Opinion Call fee as a credit to any future consultations with Natural Heart Doctor, should you choose them.

Will my insurance cover the cost of a Natural Heart Doctor Online Second Opinion?

Most likely, no. Most health plans do not cover online second opinions or consultations. You are responsible for the cost of our second opinion. Natural Heart Doctor cannot file a claim with your insurance carrier, nor can we provide a procedure (CPT) code for this service.

What is the timeline to receive an online second opinion?

We do our best to schedule your second opinion as quickly as possible. Typically, it takes 5 to 7 business days after your information has been collected to receive your phone or video online second opinion.

What information do you need in advance of our call?

Our office will send you a short questionnaire to complete and return. We DO NOT need your complete medical records.

How many questions can I ask the expert during our call?

You may ask a maximum of five questions. This is to ensure that the expert has sufficient time to devote to each question. All questions must be finalized before your online meeting.

What should I expect to receive once my second opinion is complete?

You will receive a summary of our discussion along with our second opinion. The second opinion will be in written form. After you have reviewed the second opinion, a Natural Heart Doctor clinician will follow up with you by phone to address general medical questions about the information provided in the second opinion.

What if I have follow-up questions for the expert after I have reviewed my second opinion?

If you have a clarifying question about an expert’s response to one of the questions in your second opinion, and the Natural Heart Doctor clinician is unable to address it, then you may request a follow up session for an additional fee. 

Is my medical and payment information secure?

Natural Heart Doctor is strongly committed to protecting the privacy and security of all our patients. Our website meets all federal requirements for protecting personal health information under the Health Insurance Portability and Accountability Act (HIPAA). All financial transactions are processed by Natural Heart Doctor securely using industry standard payment processing tools.

I would rather visit Natural Heart Doctor for an in-person appointment. What should I do next?

If you would prefer an in-person appointment at Natural Heart Doctor instead of an online second opinion, please call (480) 535-6844 for details and scheduling.

Can I schedule a follow up appointment with the specialist who provided my online second opinion?

Yes, we’re happy to help you on an extended basis. Our clinician can discuss options with you when presenting our second opinion summary.