LIVER CLEANSE PROTOCOL - TO SUPPORT OPTIMAL HEART HEALTH AND LONGEVITY

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LIVER CLEANSE PROTOCOL

The liver is not just a detox organ.

It is a metabolic command center.

You cannot have optimal heart health without optimal liver health.

WHAT IS THE LIVER

The liver is the largest internal organ and one of the most metabolically active tissues in the human body. It sits in the right upper abdomen beneath the rib cage and processes everything absorbed from the digestive tract.

The liver:

  • Converts vitamin D into 25-hydroxyvitamin D
  • Converts T4 into active T3 thyroid hormone
  • Regulates blood sugar through glycogen storage and release
  • Manufactures cholesterol and lipoproteins
  • Produces bile for fat emulsification
  • Eliminates cholesterol through bile
  • Processes estrogen, progesterone, cortisol, and testosterone
  • Produces albumin
  • Produces clotting factors
  • Converts ammonia into urea
  • Regulates iron and ferritin
  • Houses immune cells called Kupffer cells
  • Produces ketones during fasting
  • Synthesizes phospholipids and creatine
  • Neutralizes toxins
  • Controls inflammation

When the liver struggles, cardiovascular risk rises.

Triglycerides increase.
Insulin resistance worsens.
Estrogen accumulates.
Vitamin D drops.
Thyroid conversion falters.
Inflammation accelerates.

WHAT IS THE GALLBLADDER

The gallbladder stores and concentrates bile produced by the liver.

Bile is essential for:

  • Fat digestion
  • Absorption of vitamins A, D, E, and K
  • Elimination of cholesterol
  • Removal of toxins

When bile becomes thick and stagnant, gallstones form.

Gallstones and gallbladder dysfunction do not occur randomly.

They are driven by metabolic dysfunction.

Too much bad stuff.
Not enough good stuff.

Too much bad stuff:

  • Refined carbohydrates
  • Sugar
  • Seed oils
  • Ultra-processed foods
  • Alcohol
  • Pesticides
  • Plastics
  • Fragrance chemicals
  • Mold toxins
  • Chronic stress
  • Circadian disruption

Not enough good stuff:

  • Nutrient-dense whole foods
  • Bitter greens
  • Sulfur-rich vegetables
  • Omega-3 fatty acids
  • Fat-soluble vitamins
  • Sunlight
  • Movement
  • Parasympathetic activation

The answer is not removing the gallbladder (and if yours is gone, this article still applies).
Removing the organ does not correct the metabolic dysfunction that created the problem.

Here is the Natural Heart Doctor method to restore liver and gallbladder function.

1. EAT WELL

Foundation first.

Focus on:

100 percent organic food

  • Pasture-raised meats
  • Organ meats including liver and heart
  • Wild-caught seafood
  • Wild salmon roe
  • Pasture-raised eggs for choline
  • Bitter greens for bile stimulation
  • Cruciferous vegetables for detox support
  • Garlic and onions for sulfur
  • Olives, avocado and coconut
  • Fermented foods

Seaweed

Cacao

Raw honey and maple syrup

Organic coffee

Remove completely during active repair:

  • Alcohol
  • Seed oils
  • Refined sugar
  • Ultra-processed food
  • Artificial sweeteners
  • Conventional pesticide-heavy produce

Real food restores bile quality and liver function.

2. LIVE WELL

Get Sleep

Get Sunshine

Get Moving

Get Chiropractic Care

Avoid hepatotoxic exposures:

  • Glyphosate
  • Plastics
  • Statin drugs and other prescription medications like antibiotics, antacids
  • OTC meds such as acetaminophen
  • Mold and bacteria from water damage buildings
  • Heavy metals

Prioritize:

  • Early bedtime, ideally soon after sundown
  • Morning sunlight
  • Clean filtered water
  • Daily movement
  • Sweating via sauna or exercise
  • Time outdoors

Circadian rhythm regulates nighttime liver repair.

3. THINK WELL

Chronic stress elevates cortisol and insulin, driving fatty liver and inflammation.

Daily parasympathetic practices:

  • Prayer
  • Breath work
  • Time outdoors
  • Community
  • Reduced digital overload
  • Gratitude

The nervous system influences liver metabolism.

4. TEST DON’T GUESS

Just like the metrics of the gas tank meter in your car and your bank account status, the metrics of health are critical. Assess comprehensively with the CHAT panel.

Swiffer test

Gut Zoomer

5. EVIDENCE-BASED SUPPLEMENT SUPPORT

Whole food first.

Kickstart My Heart
New Zealand grass-fed elk liver, kidney, and heart.
Provides B vitamins, retinol, copper, selenium, CoQ10, peptides, and mitochondrial support.

Wild Salmon Roe
Provides omega-3 phospholipids to reduce inflammation, support triglyceride balance, and improve hepatic fat metabolism.

OptiLipid with silymarin, berberine and more
Supports lipid balance and oxidative stress reduction, addressing metabolic drivers of fatty liver.

There is no drug deficiency causing fatty liver.
There is metabolic dysfunction.

6. SUPPORT THE GUT-LIVER AXIS

The gut and liver communicate directly through the portal vein.

If the gut is inflamed, the liver is inflamed.

Address:

  • Dysbiosis
  • Intestinal permeability
  • Mold toxins
  • Endotoxin load
  • Food sensitivities

Natural Heart Doctor method:

  • Bone broth
  • Fermented foods
  • Removal of inflammatory triggers
  • Fiber from whole vegetables

Heart Helpers probiotic supports microbial balance and reduces endotoxin burden.

7. BIOHACKING STRATEGIES

Adjunctive, not foundational.

Coffee Enemas with Cardiology Coffee

Purpose:

  • Stimulate bile flow
  • Increase glutathione activity
  • Enhance hepatic circulation

Protocol:

Use organic mold-free coffee. Brew and cool to body temperature. Retain 10 to 15 minutes if tolerated. Begin once weekly.

Ozone Suppositories

Purpose:

  • Support mitochondrial signaling
  • Enhance antioxidant upregulation
  • Improve oxygen delivery

Use once daily for 2-4 weeks after a bowel movement

Castor Oil Liver Pack

Purpose:

  • Increase lymphatic flow
  • Support parasympathetic activation
  • Improve circulation

Protocol:

Apply organic castor oil over the right upper abdomen. Cover with cloth. Apply gentle heat for 30 to 45 minutes. Use 3 to 4 times weekly.

Sauna Therapy

  • 15 to 25 minutes sauna
  • Cool rinse
  • Repeat if tolerated

Supports circulation and detox pathways.

Coffee Timing

Morning coffee aligned with circadian rhythm is preferred. Avoid late-day caffeine to protect sleep, as liver repair is strongest at night.

FINAL MESSAGE

Fatty liver is reversible.
Gallbladder dysfunction is often reversible.
Metabolic dysfunction is correctable.

Correct the inputs.
Support the detox pathways.
Restore mitochondrial function.
Heal the gut.

When the liver heals:

  • Inflammation drops.
  • Triglycerides fall.
  • Insulin improves.
  • Vitamin D normalizes.
  • Hormones balance.
  • Cardiovascular risk declines.

Heal the liver.
Protect the heart.
Support longevity.

Want guided support? Work with us. I suggest starting with a health coach consultation. Learn more here.

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About Dr. Keith Smigiel NP, DC

Dr. Keith Smigiel

Dr. Keith Smigiel is a regenerative medicine physician and pain management specialist. He takes an integrative approach to medicine, focusing on customized solutions tailored to individual needs. Using advanced, non-surgical treatments, Dr. Smigiel stimulates your body’s ability to naturally heal itself.

Dr. Smigiel helps people suffering from conditions such as chronic pain and erectile dysfunction, to hair loss and weight gain. Combining treatments such as PRP Therapy, Ozone, Neural Prolotherapy, and IV Infusions with functional rehabilitation, he helps you look and feel better.

He heals the body, instead of just treating the symptoms!

With his professional qualifications as a certified family nurse practitioner, a doctor of chiropractic, and a fellow of the International Academy of Medical Acupuncture, Dr. Smigiel offers patients comprehensive care from a broad perspective of conventional and alternative medicine. He also has extensive experience in functional rehabilitation and chronic pain management.

Dr. Smigiel is married to Angela and has two children, Sophia and Larz. When he’s not busy helping patients, he enjoys hiking, mountain biking, motocross, and boating.

About Dr. Lauren Lattanza NMD, FACC

Dr. Lattanza Office Visit with Patient

As a Naturopathic Physician, I am trained to treat the whole person and get to the root cause of disease.

I went to Arizona State University where I graduated with a bachelor’s degree in psychology with a depth in physiology and minor in Spanish. After my undergraduate degree I was working on prerequisite classes towards medical school, which is when I came to learn that my values identified best with the principles of naturopathic medicine. I knew that I wanted to help patients identify the causes of disease and be able to offer treatments which would improve their health rather than simply treating symptoms.

I dedicated the next 4 years to the Southwest College of Naturopathic Medicine in Tempe, Arizona where I attained my Doctorate of Naturopathic Medicine. I served as Class President all 4 years, Board of Trustees – Student Trustee, spoke as the Club President for our branch of Toastmasters, and was voted by my peers and attending physicians to earn the Outstanding Leadership Award for the Class of 2020. Throughout medical school I took it upon myself to work alongside MDs, DOs, chiropractors, and functional medicine practitioners in addition to naturopathic physicians.

As a Spanish speaking student, I was able to volunteer with community clinics around Phoenix and provide free healthcare to low-income families. Due to this combined exposure, I came to find my passion in treating cardiometabolic and digestive disorders that are all too common, yet largely preventable. I took the opportunity to learn the broad spectrum of healthcare so I can ensure that I am able to provide my patients with the best options.

About Dr. Jack Wolfson DO, FACC

Dr. Wolfson Office Visit with Patient

Dr. Jack Wolfson is a cardiologist, Amazon best-selling author, husband, father, and the nation’s #1 Natural Heart Doctor.

For more than two decades, more than one million people have enjoyed the warmth, compassion, and transformational power of his natural heart health courses and events.

Dr. Wolfson is the founder of Natural Heart Doctor Scottsdale, his heart health practice in Arizona, and Natural Heart Doctor, an online resource center with natural health information. Doctors from across the globe reach out to Dr. Wolfson for training and education in holistic health practices.

He has been named one of America’s Top Functional Medicine Doctors and is a five-time winner of the Natural Choice Awards as a holistic M.D. Dr. Wolfson’s work has been covered by more than 100 media outlets, including NBC, CNN, and the Washington Post. His book “The Paleo Cardiologist: The Natural Way to Heart Health” was an Amazon #1 best-seller.

Dr. Wolfson and his wife Heather have four children and are committed to making the world a better place to live. They provide for those in need (including animals) and support natural health causes through their philanthropic efforts.

Chiropractic

Our chiropractor is an expert at adjustments and holistic chiropractic care and works closely in conjunction with the other health care experts at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

IV Therapy

We use specially formulated natural vitamins and minerals that are injected into a vein to prevent or treat dehydration. Ideal for people in Arizona.

Call (480) 535-6844 for details and scheduling.

Acupuncture

Stimulate your body’s natural healing abilities and promote physical and emotional well-being with acupuncture at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

Health Coaching

Our health coaches use evidence based skillful conversation, clinical interventions, and strategies to engage you actively and safely in health behavior changes.

Call (480) 535-6844 for details and scheduling.

Cardio Tests

We use the most advanced testing in the world to assess heart health and to identify the root cause of your health issues.

Call (480) 535-6844 for details and scheduling.

Office Visits

Schedule an office visit with one of our cardiologists, holistic physicians, chiropractor, or health coaches.

Call (480) 535-6844 for details and scheduling.

Frequently Asked Questions

I’d like to receive an online second opinion from Natural Heart Doctor. What do I do next?

You can initiate a second opinion online through our website at any time. To begin, select the team member you’d like to speak with and open an account.

Click here for cardiologist Dr. Jack Wolfson.

Naturopathic Medical Doctor Dr. Lauren Lattanza. Get details.

Naturopathic Medical Doctor Dr. Tonia Rainier. Get details.

Click here for  Natural Heart Doctor Health Coach.

Alternatively, you can email health@naturalheartdoctor.com. A member of our care team will help guide you through the process of starting a second opinion.

What is the cost of a Natural Heart Doctor Online Second Opinion?

The cost for most second opinions varies by team member. This fee includes information collection, a phone or video consultation, a second opinion from a Natural Heart Doctor specialist and guidance throughout the process from your personal Care Team at Natural Heart Doctor.

Cardiologist Dr. Jack Wolfson’s Second Opinion Fee is $1500.

Holistic Physician’s Dr. Lauren Lattanza’s Second Opinion Fee is $250.

Naturopathic Physician Dr. Tonia Rainier’s Second Opinion Fee is $250.

Note: We apply the Online Second Opinion Call fee as a credit to any future consultations with Natural Heart Doctor, should you choose them.

Will my insurance cover the cost of a Natural Heart Doctor Online Second Opinion?

Most likely, no. Most health plans do not cover online second opinions or consultations. You are responsible for the cost of our second opinion. Natural Heart Doctor cannot file a claim with your insurance carrier, nor can we provide a procedure (CPT) code for this service.

What is the timeline to receive an online second opinion?

We do our best to schedule your second opinion as quickly as possible. Typically, it takes 5 to 7 business days after your information has been collected to receive your phone or video online second opinion.

What information do you need in advance of our call?

Our office will send you a short questionnaire to complete and return. We DO NOT need your complete medical records.

How many questions can I ask the expert during our call?

You may ask a maximum of five questions. This is to ensure that the expert has sufficient time to devote to each question. All questions must be finalized before your online meeting.

What should I expect to receive once my second opinion is complete?

You will receive a summary of our discussion along with our second opinion. The second opinion will be in written form. After you have reviewed the second opinion, a Natural Heart Doctor clinician will follow up with you by phone to address general medical questions about the information provided in the second opinion.

What if I have follow-up questions for the expert after I have reviewed my second opinion?

If you have a clarifying question about an expert’s response to one of the questions in your second opinion, and the Natural Heart Doctor clinician is unable to address it, then you may request a follow up session for an additional fee. 

Is my medical and payment information secure?

Natural Heart Doctor is strongly committed to protecting the privacy and security of all our patients. Our website meets all federal requirements for protecting personal health information under the Health Insurance Portability and Accountability Act (HIPAA). All financial transactions are processed by Natural Heart Doctor securely using industry standard payment processing tools.

I would rather visit Natural Heart Doctor for an in-person appointment. What should I do next?

If you would prefer an in-person appointment at Natural Heart Doctor instead of an online second opinion, please call (480) 535-6844 for details and scheduling.

Can I schedule a follow up appointment with the specialist who provided my online second opinion?

Yes, we’re happy to help you on an extended basis. Our clinician can discuss options with you when presenting our second opinion summary.