As a board-certified holistic cardiologist, I’m always seeking evidence-based, natural approaches to prevent and reverse cardiovascular disease. One of the most promising discoveries is nattokinase (NK), a powerful enzyme derived from *natto*, a traditional Japanese fermented soybean dish. First identified in 1987 by Dr. Hiroyuki Sumi, nattokinase offers an impressive array of cardiovascular benefits, including its ability to combat high blood pressure, dissolve dangerous blood clots, lower cholesterol, and prevent plaque buildup in arteries.
Why Nattokinase?
Nattokinase is a fibrinolytic enzyme, meaning it helps break down fibrin, a protein involved in blood clot formation. By doing so, it enhances blood flow and reduces the risk of clot-related conditions such as stroke and heart attack. Studies suggest that the longevity of the Japanese population is partially due to their regular consumption of natto, which is rich in nattokinase. This enzyme is now gaining global recognition as a natural supplement to address atherosclerosis and its associated risks.
How Does Nattokinase Reverse Artery Disease?
1. Reducing Carotid Intima-Media Thickness (CIMT):
CIMT measures the thickness of the inner two layers of the carotid artery and is a key indicator of atherosclerosis. In a recent landmark study involving 1,062 participants, daily supplementation with a high dose of nattokinase (10,800 fibrinolytic units) led to a remarkable 20% reduction in CIMT after 12 months. This significant improvement underscores nattokinase’s potential to reverse arterial thickening and improve vascular health.
2. Shrinking Carotid Plaque Size:
The same study revealed that nattokinase supplementation reduced carotid plaque size by over 30%. Plaque buildup is a major contributor to heart attacks and strokes, as it can restrict blood flow or rupture, causing clots. By reducing plaque size, nattokinase directly addresses the root cause of many cardiovascular events.
3. Lipid-Lowering Effects:
Nattokinase has been shown to improve lipid profiles by significantly lowering triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), while increasing protective high-density lipoprotein cholesterol (HDL-C). This dual action reduces the likelihood of plaque formation and supports overall heart health.
4. Anti-Oxidative and Anti-Inflammatory Properties:
Nattokinase prevents the oxidation of LDL cholesterol, a key step in plaque development. Its antioxidant and anti-inflammatory effects further protect the arteries from damage, promoting long-term cardiovascular resilience.
Safe, Natural, and Effective
One of the most compelling aspects of nattokinase is its safety profile. In the study, even at a high dose of 10,800 FU/day, participants experienced no significant adverse effects. Combined with regular exercise, a heart-healthy diet, and synergistic nutrients like vitamin K2, nattokinase can transform arterial health naturally.
A Holistic Approach to Cardiovascular Health
If you’re looking to prevent or reverse carotid and coronary artery disease, nattokinase is a natural, scientifically-supported tool to include in your wellness arsenal. Paired with a lifestyle rooted in clean nutrition, regular movement, and stress management, nattokinase empowers your journey to a 100-Year Heart. Consult with your healthcare provider to determine the best dose for your unique needs, and embrace the power of nature to heal and protect your heart.
My recommendations
Follow the 100 Year Heart Method of Eat Well, Live Well, Think Well. Test, Don’t Guess and evidence-based supplements.
Our nattokinase product includes serrapeptase. We call it Flow. All you need is one cap, 2x per day. You can also go to 2 caps 2x per day. Take away from food.
One More Thing
For extra impact on plaque reversal with supplements, see Arterosil 1 cap 2x per day AND Australian Emu Oil, 2 caps daily for vitamins such as K2.
