12 things in your home that Lead to Heart Disease
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Oxidized LDL (OxLDL): The Risk Factor You Need to Know

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Cholesterol blocked artery with heart. 3d illustration

LDL is NOT bad. LDL is good. LDL is a beautiful molecule. A miracle actually. LDL is so critical, all mammals manufacture it. But Pharma and the doctor’s it controls demonized LDL. They told us it was the “bad cholesterol”. Nothing could be further from the truth. 

But LDL can turn bad, by undergoing a change from a process called oxidation. Think of oxidation like the rusting of an old car. And it is the oxidation that leads to damage from LDL. 

Oxidized low-density lipoprotein (LDL) is a key factor in the development of atherosclerosis, a process leading to cardiovascular diseases such as heart attacks, stroke, and coronary artery disease. LDL particles are crucial components of the body’s lipid transport system, but when they undergo oxidation, they can become harmful.

LDL particles are composed of a core of lipids, including cholesterol and triglycerides, surrounded by a shell of proteins, phospholipids, and cholesterol. The oxidation of LDL involves the modification of its lipid and protein components through oxidative stress, a process that occurs when there’s an imbalance between the production of reactive oxygen species (free radicals) and the body’s ability to detoxify their harmful effects through neutralization by antioxidants.

Ox LDL, Coronary Artery Disease and Heart Attacks

Oxidized LDL (oxLDL) has been implicated in the pathogenesis of atherosclerosis. It is thought to contribute to the formation of atherosclerotic plaques by promoting the accumulation and oxidation of LDL in the arterial wall. These oxLDL particles are recognized by scavenger receptors on macrophages, leading to the formation of foam cells, a hallmark of early atherosclerotic lesions.

Several studies have highlighted the role of oxidized LDL in cardiovascular diseases. For instance, elevated levels of oxLDL have been linked to an increased risk of heart attacks. This association is due to the inflammatory and endothelial-damaging effects of oxLDL, contributing to plaque instability and rupture, leading to myocardial infarction.

Coronary artery calcification, another critical aspect of cardiovascular disease, has also been linked to oxidized LDL. The calcification process is influenced by oxLDL through its ability to stimulate vascular smooth muscle cells and contribute to the formation of calcified plaques, which are a significant predictor of future cardiovascular events.

Ox LDL and High Blood Pressure

It appears that the oxidative stress process affects blood vessels. When they undergo these changes, arterial stiffness is the end result. In fact, a study from several years ago was the first to show oxidative stress is linked to arterial stiffness. Stiff arteries lead to high blood pressure, stroke, kidney disease and heart failure. 

Ox LDL and Stroke

Moreover, oxidized LDL has been connected with the progression of stroke. It exacerbates the process of atherosclerosis in cerebral arteries, increasing the risk of cerebral ischemia. If you have high oxLDL and have already suffered a stroke, your risk of dying is higher than someone without ox LDL, according to this study. (Test your oxidative stress here). 

Ox LDL and AFIB

Lastly, there is emerging evidence suggesting a link between oxidized LDL and atrial fibrillation, a common cardiac arrhythmia. OxLDL may contribute to atrial structural remodeling and fibrosis, thereby increasing the susceptibility to atrial fibrillation, as found in this 2016 study

Test, Don’t Guess

We have the perfect test for you to see if you have oxLDL particles. It is called lipid peroxides, a urine test done in the comfort of your home. 

Just click this link to purchase your test and we will ship it right out to you. Then, when the results are back after a couple weeks, you get a free review call with an NHD health coach.

But don’t worry. If you have ox LDL, we are ready to help you reverse this condition.

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About Dr. Keith Smigiel NP, DC

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Dr. Keith Smigiel is a regenerative medicine physician and pain management specialist. He takes an integrative approach to medicine, focusing on customized solutions tailored to individual needs. Using advanced, non-surgical treatments, Dr. Smigiel stimulates your body’s ability to naturally heal itself.

Dr. Smigiel helps people suffering from conditions such as chronic pain and erectile dysfunction, to hair loss and weight gain. Combining treatments such as PRP Therapy, Ozone, Neural Prolotherapy, and IV Infusions with functional rehabilitation, he helps you look and feel better.

He heals the body, instead of just treating the symptoms!

With his professional qualifications as a certified family nurse practitioner, a doctor of chiropractic, and a fellow of the International Academy of Medical Acupuncture, Dr. Smigiel offers patients comprehensive care from a broad perspective of conventional and alternative medicine. He also has extensive experience in functional rehabilitation and chronic pain management.

Dr. Smigiel is married to Angela and has two children, Sophia and Larz. When he’s not busy helping patients, he enjoys hiking, mountain biking, motocross, and boating.

About Dr. James Kneller, M.D., Ph.D., FHRS

Dr. James Kneller, M.D., Ph.D., FHRS

Dr. James Kneller is one of the nation’s leading heart rhythm specialists. Dr. Kneller is certified by the American Board of Internal Medicine (ABIM) in Clinical Cardiac Electrophysiology, Cardiovascular Disease, and Internal Medicine.

As a Fellow of the Heart Rhythm Society (FHRS) and Certified Cardiac Device Specialist (CCDS), Kneller provides comprehensive patient care, combining best medical practice with invasive procedures using state-of-the-art technologies to treat heart rhythm disorders.

Beyond guideline-directed therapies, Kneller is passionate about optimized personal health. With a deep interest in complimentary alternative medicine (CAM), he strives to reduce the need for pharmaceuticals, invasive procedures, and exposure to harmful radiation. With Natural Heart Doctor, he strives to help each and every client to Live Well, Eat Well, and Think Well to attain their 100-year heart!

About Dr. Lauren Lattanza NMD, FACC

Dr. Lattanza Office Visit with Patient

As a Naturopathic Physician, I am trained to treat the whole person and get to the root cause of disease.

I went to Arizona State University where I graduated with a bachelor’s degree in psychology with a depth in physiology and minor in Spanish. After my undergraduate degree I was working on prerequisite classes towards medical school, which is when I came to learn that my values identified best with the principles of naturopathic medicine. I knew that I wanted to help patients identify the causes of disease and be able to offer treatments which would improve their health rather than simply treating symptoms.

I dedicated the next 4 years to the Southwest College of Naturopathic Medicine in Tempe, Arizona where I attained my Doctorate of Naturopathic Medicine. I served as Class President all 4 years, Board of Trustees – Student Trustee, spoke as the Club President for our branch of Toastmasters, and was voted by my peers and attending physicians to earn the Outstanding Leadership Award for the Class of 2020. Throughout medical school I took it upon myself to work alongside MDs, DOs, chiropractors, and functional medicine practitioners in addition to naturopathic physicians.

As a Spanish speaking student, I was able to volunteer with community clinics around Phoenix and provide free healthcare to low-income families. Due to this combined exposure, I came to find my passion in treating cardiometabolic and digestive disorders that are all too common, yet largely preventable. I took the opportunity to learn the broad spectrum of healthcare so I can ensure that I am able to provide my patients with the best options.

About Dr. Jack Wolfson DO, FACC

Dr. Wolfson Office Visit with Patient

Dr. Jack Wolfson is a board-certified cardiologist, Amazon best-selling author, husband, father, and the nation’s #1 Natural Heart Doctor.

For more than two decades, more than one million people have enjoyed the warmth, compassion, and transformational power of his natural heart health courses and events.

Dr. Wolfson is the founder of Natural Heart Doctor Scottsdale, his heart health practice in Arizona, and Natural Heart Doctor, an online resource center with natural health information. Doctors from across the globe reach out to Dr. Wolfson for training and education in holistic health practices.

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Dr. Wolfson and his wife Heather have four children and are committed to making the world a better place to live. They provide for those in need (including animals) and support natural health causes through their philanthropic efforts.

Chiropractic

Our chiropractor is an expert at adjustments and holistic chiropractic care and works closely in conjunction with the other health care experts at Natural Heart Doctor.

Call (480) 535-6844 for details and scheduling.

IV Therapy

We use specially formulated natural vitamins and minerals that are injected into a vein to prevent or treat dehydration. Ideal for people in Arizona.

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Acupuncture

Stimulate your body’s natural healing abilities and promote physical and emotional well-being with acupuncture at Natural Heart Doctor.

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Health Coaching

Our health coaches use evidence based skillful conversation, clinical interventions, and strategies to engage you actively and safely in health behavior changes.

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Cardio Tests

We use the most advanced testing in the world to assess heart health and to identify the root cause of your health issues.

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Office Visits

Schedule an office visit with one of our cardiologists, holistic physicians, chiropractor, or health coaches.

Call (480) 535-6844 for details and scheduling.

Frequently Asked Questions

I’d like to receive an online second opinion from Natural Heart Doctor. What do I do next?

You can initiate a second opinion online through our website at any time. To begin, select the team member you’d like to speak with and open an account.

Click here for cardiologist Dr. Jack Wolfson.

Naturopathic Medical Doctor Dr. Lauren Lattanza. Get details.

Naturopathic Medical Doctor Dr. Tonia Rainier. Get details.

Click here for  Natural Heart Doctor Health Coach.

Alternatively, you can email health@naturalheartdoctor.com. A member of our care team will help guide you through the process of starting a second opinion.

What is the cost of a Natural Heart Doctor Online Second Opinion?

The cost for most second opinions varies by team member. This fee includes information collection, a phone or video consultation, a second opinion from a Natural Heart Doctor specialist and guidance throughout the process from your personal Care Team at Natural Heart Doctor.

Cardiologist Dr. Jack Wolfson’s Second Opinion Fee is $1500.

Holistic Physician’s Dr. Lauren Lattanza’s Second Opinion Fee is $250.

Naturopathic Physician Dr. Tonia Rainier’s Second Opinion Fee is $250.

Note: We apply the Online Second Opinion Call fee as a credit to any future consultations with Natural Heart Doctor, should you choose them.

Will my insurance cover the cost of a Natural Heart Doctor Online Second Opinion?

Most likely, no. Most health plans do not cover online second opinions or consultations. You are responsible for the cost of our second opinion. Natural Heart Doctor cannot file a claim with your insurance carrier, nor can we provide a procedure (CPT) code for this service.

What is the timeline to receive an online second opinion?

We do our best to schedule your second opinion as quickly as possible. Typically, it takes 5 to 7 business days after your information has been collected to receive your phone or video online second opinion.

What information do you need in advance of our call?

Our office will send you a short questionnaire to complete and return. We DO NOT need your complete medical records.

How many questions can I ask the expert during our call?

You may ask a maximum of five questions. This is to ensure that the expert has sufficient time to devote to each question. All questions must be finalized before your online meeting.

What should I expect to receive once my second opinion is complete?

You will receive a summary of our discussion along with our second opinion. The second opinion will be in written form. After you have reviewed the second opinion, a Natural Heart Doctor clinician will follow up with you by phone to address general medical questions about the information provided in the second opinion.

What if I have follow-up questions for the expert after I have reviewed my second opinion?

If you have a clarifying question about an expert’s response to one of the questions in your second opinion, and the Natural Heart Doctor clinician is unable to address it, then you may request a follow up session for an additional fee. 

Is my medical and payment information secure?

Natural Heart Doctor is strongly committed to protecting the privacy and security of all our patients. Our website meets all federal requirements for protecting personal health information under the Health Insurance Portability and Accountability Act (HIPAA). All financial transactions are processed by Natural Heart Doctor securely using industry standard payment processing tools.

I would rather visit Natural Heart Doctor for an in-person appointment. What should I do next?

If you would prefer an in-person appointment at Natural Heart Doctor instead of an online second opinion, please call (480) 535-6844 for details and scheduling.

Can I schedule a follow up appointment with the specialist who provided my online second opinion?

Yes, we’re happy to help you on an extended basis. Our clinician can discuss options with you when presenting our second opinion summary.